Lymphatic Anomalies

The lymphatic malformation is a group of the lymphatic disorders, that include conditions such as Generalized Lymphatic Anomaly, Kaposiform Lymphangiomatosis and Gorham-Stout Disease. More detailed classification of these disorders, can be found on the website of the International Society for Study of the Vascular Anomalies (ISSVA).

In these diseases, the lymphatic masses involve multiple organs, including bones, liver, spleen and soft tissue. However, the most significant mortality and morbidity in these diseases is associated with involvement of the lungs.

In some of these patients the abnormal lymphatic masses extend into the pleural space and result in overflow of the lymphatic fluid into the lung parenchyma, that result in pleural effusions and interstitial lung disease. These two conditions can in turn result in deterioration of the pulmonary function.

In patient with lymphatic malformation and lung involvement, we initially perform DCMRL, to identify the underline anatomy and pathology. In cases where we identify the abnormal lymphatic flow to the lung parenchyma, we can perform the lymphatic embolization, either TDE or interstitial embolization or combination of both.